An article in posted by the Los Angeles Times today cites a neurologist who believes that Pio Pico, governor of pre-statehood California during the 1830s and 1840s, may have been afflicated by a neurological disorder that distorted his physical features and made him impotent for much of his life.
The docotor consulted historians and hisotorical images of Pico to verify his speculations, noting that the disorder appears to have ceased affecting Pico by his late 50s.